Fig. 1.

Selective elevation of dietary LNA elevates liver endocannabinoids in mice fed low fat diets (LFD) of 12.5 en% fat (light gray) and medium fat diets (MFD) of 35 en% fat (dark gray). Increasing dietary LNA from 1 en% (open bars) to 8 en% (hatched bars) in both LFD and MFD elevated (a) liver 2-AG and (b) AEA, an increase that was not observed in the cerebral cortex (c, d). Different superscript letters indicate a statistical significance p < 0.05 by ANOVA, n = 8–9