Fig. 5.

a 5 × 10³ MS-1 cells of 410.4-vec, 410.4shEP4, 410 or 67 cells (black bars) were re-plated in secondary (MS-2) cultures and on day 10, sphere number and cellularity were determined for MS-2 cultures. Mean ± SE. b–e MDA-MB-231 cells placed in mammosphere culture and on day 2, treated with Indomethacin, AH23848, Frondoside A or RQ-15986 at the indicated concentrations. On day 10, sphere number and cellularity were determined