Table 2.

Summary of statistical results of different metabolites in various limbic regions with age using Pearson correlation

Region	Cho		Cr		NAA		mI
	r	p	r	p	r	p	r	p
ACC	0.545**	0.002 ↑	0.571**	0.001 ↑	0.674**	<0.001 ↑	0.254	0.192 −
PCC	0.614**	<0.001 ↑	0.670**	<0.001 ↑	0.528**	0.003 ↑	0.179	0.344 −
Left hippocampus	0.283	0.129 −	0.130	0.492 −	0.409*	0.025 ↑	0.289	0.122 −
Right hippocampus	0.004	0.983 −	0.258	0.169 −	0.076	0.692 −	−0.024	0.902 –

ACC anterior cingulate cortex, Cho choline, Cr creatine, mI myo-inositol, NAA N-acetyl-aspartate, PCC posterior cingulate cortex, ↑ significant increase, − no significant change

*p < 0.05, **p < 0.01