Table 1.
Cross-sectional analysis of the genotypic and allelic frequencies of SIRT3 single nucleotide polymorphisms rs3825075, rs4980329, and rs11555236
| SNP (no.) | Genotype no. (%) | Allele no. (%) | ||||||
|---|---|---|---|---|---|---|---|---|
| ≤85y | >85y | χ 2 statistics | ≤85y | >85y | χ 2 statistics | |||
| rs3825075 (n = 549) | GG | 136 (43.9) | 117 (48.9) | χ 2 = 3.1; df = 2; p = 0.21 | G | 418 (67.4) | 329 (68.8) | χ 2 = 0.24; df = 1; p = 0.62 |
| GA | 146 (47.1) | 95 (37.4) | A | 202 (32.6) | 149 (31.2) | |||
| AA | 28 (9.0) | 27 (13.7) | ||||||
| rs4980329 (n = 542) | GG | 167 (54.7) | 138 (58.2) | χ 2 = 2.0; df = 2; p = 0.37 | G | 458 (75.1) | 360 (75.9) | χ 2 = 0.10; df = 1; p = 0.74 |
| GA | 124 (40.6) | 84 (35.4) | A | 152 (24.9) | 114 (24.1) | |||
| AA | 14 (4.7) | 15 (6.4) | ||||||
| rs11555236 (n = 542) | GG | 169 (54.9) | 137 (58.5) | χ 2 = 2.5; df = 2; p = 0.28 | G | 454 (73.7) | 361 (77.1) | χ 2 = 1.7; df = 1; p = 0.19 |
| GT | 116 (37.7) | 87 (37.2) | T | 162 (26.3) | 107 (22.9) | |||
| TT | 23 (7.4) | 10 (4.3) | ||||||
no. number, 85y 85 years of age, df degree of freedom, p p value