Table 3.

Odds (95 % CI) of frailty associated with ADMA by atherosclerotic diseases status

	Atherosclerotic diseases
	No (n = 1,104)		p value	Yes (n = 183)		p value
	OR	95 % CI		OR	95 % CI
Model 1a
For 1 SD increase	1.18	(1.07–1.31)	0.001	0.97	(0.83–1.14)	0.735
Quartiles	Ref			Ref
	1.27	(0.58–2.79)	0.551	1.26	(0.42–3.73)	0.679
	1.70	(0.79–3.65)	0.173	0.81	(0.27–2.45)	0.713
	2.85	(1.40–5.83)	0.004	0.80	(0.28–2.58)	0.778
p for trend			0.001			0.619
Model 2b
For 1 SD increase	1.13	(1.01–1.26)	0.032	0.91	(0.76–1.10)	0.324
Quartiles	Ref			Ref
	1.00	(0.44–2.26)	0.995	1.28	(0.41–4.02)	0.668
	1.26	(0.57–2.78)	0.564	0.69	(0.22–2.20)	0.529
	2.07	(0.99–4.33)	0.055	0.66	(0.21–2.15)	0.494
p for trend			0.022			0.342
Model 3c
For 1 SD increase	1.12	(1.00–1.25)	0.049	0.89	(0.73–1.10)	0.286
Quartiles	Ref			Ref
	1.08	(0.47–2.51)	0.859	1.72	(0.49–6.06)	0.402
	1.46	(0.64–3.31)	0.368	0.62	(0.17–2.29)	0.475
	2.06	(0.94–4.49)	0.070	0.65	(0.18–2.40)	0.519
p for trend			0.032			0.342
Model 4d
For 1 SD increase	1.14	(1.01–1.28)	0.032	0.84	(0.67–1.04)	0.110
Quartiles	Ref			Ref
	0.88	(0.37–2.13)	0.782	1.90	(0.51–7.11)	0.341
	1.51	(0.66–3.44)	0.328	0.56	(0.14–2.28)	0.422
	2.09	(0.95–4.61)	0.067	0.39	(0.09–1.69)	0.207
p for trend			0.018			0.104
Model 5e
For 1 SD increase	1.35	(1.02–1.79)	0.035	0.64	(0.38–1.10)	0.105
Quartiles	Ref			Ref
	0.87	(0.36–2.09)	0.749	2.07	(0.55–7.71)	0.280
	1.45	(0.63–3.31)	0.382	0.49	(0.12–1.99)	0.315
	2.05	(0.92–4.51)	0.076	0.39	(0.09–1.70)	0.210
p for trend			0.021			0.098

^aCrude

^bAdjusted for age

^cAdjusted for age, hypertension, hypercholesterolemia, diabetes, sex, and BMI categories

^dAdjusted for age, hypertension, hypercholesterolemia, diabetes, sex, BMI categories, and ABI categories

^eAdjusted for age, hypertension, hypercholesterolemia, diabetes, sex, BMI categories, ABI categories, and renal function