Table 1.
The genotype and allele distribution and odds ratios (OR) of the g.1289209T>C and the c.73G>A polymorphisms of the UBC9 gene in breast cancer patients and controls
| Genotype or allele | Breast cancer patients (n = 181) | Controls (n = 277) | OR | OR (95 % Cl) | P value |
|---|---|---|---|---|---|
| g.1289209T>C | |||||
| C/C | 85 | 120 | 1.00 ref. | ||
| C/T | 80 | 148 | 0.90 | 0.58–1.38 | 0.615 |
| T/T | 16 | 7 | 2.58 | 1.00–6.65 | 0.050 |
| C | 250 | 388 | 1.00 ref. | ||
| T | 112 | 162 | 1.24 | 0.87–1.77 | 0.232 |
| c.73G>A | |||||
| G/G | 52 | 228 | 1.00 ref. | ||
| G/A | 89 | 40 | 5.03 | 3.05–8.28 | <0.001 |
| A/A | 40 | 7 | 11.3 | 4.24–30.3 | <0.001 |
| G | 193 | 496 | 1.00 ref. | ||
| A | 169 | 54 | 6.86 | 4.43–10.6 | <0.001 |
| c.73G>A/g.1289209T>C | |||||
| GG/CC | 22 | 102 | 1.00 ref. | ||
| GG/CT | 25 | 119 | 0.116 | 0.063–0.211 | <0.001 |
| GG/TT | 5 | 7 | 0.471 | 0.135–1.639 | 0.236 |
| GA/CC | 41 | 15 | 3.456 | 1.64–7.283 | 0.001 |
| GA/CT | 41 | 25 | 1.439 | 0.771–2.689 | 0.253 |
| GA/TT | 7 | 0 | 5.704 | 0.671–48.488 | 0.111 |
| AA/CC | 22 | 3 | 5.227 | 1.464–18.667 | 0.011 |
| AA/CT | 14 | 4 | 7.47 | 1.58–35.31 | 0.011 |
| AA/TT | 4 | 0 | 4.686 | 0.391–56.184 | 0.223 |