Table 2.
The genotype and allele distribution and odds ratios (OR) of the g.1289209T>C and c.73G>A polymorphisms of the UBC9 gene in groups of patients with different estrogen receptor status
Genotype or allele | ER positive (n = 119) | ER negative (n = 53) | OR | OR (95 % Cl) | P value |
---|---|---|---|---|---|
g.1289209T>C | |||||
C/C | 62 | 21 | 1.00 ref. | ||
C/T | 51 | 22 | 1.07 | 0.55–2.08 | 0.852 |
T/T | 6 | 10 | 0.22 | 0.07–0.64 | 0.006 |
C | 175 | 64 | 1.00 ref. | ||
T | 63 | 42 | 0.53 | 0.32–0.88 | 0.014 |
c.73G>A | |||||
GG | 35 | 14 | 1.00 ref. | ||
GA | 58 | 27 | 0.90 | 0.47–1.74 | 0.757 |
AA | 26 | 12 | 0.95 | 0.43–2.09 | 0.903 |
G | 128 | 55 | 1.00 ref. | ||
A | 110 | 51 | 0.95 | 0.43–2.09 | 0.903 |