Table 1.
Overview of studies showing effects of antihypertensive agents on sexual function in men and women
| Effect on sexual function | Beneficial | Neutral | Negative |
|---|---|---|---|
| β-blockers |
Nebivolol: Doumas et al., 2006 Brixius et al., 2007 |
Medical Research Council, 1981 Wassertheil-Smoller et al., 1991 Rosen et al., 1994 Neaton et al., 1995 Grimm et al., 1997 Perez-Stable et al., 2000 Franzen et al., 2001 |
Bauer et al., 1978 Hogan et al., 1980 Suzuki et al., 1988 Fogari et al., 1998 Buchardt et al.,. 2000 Fogari et al., 2001 Llisteri et al., 2001 Fogari et al., 2002 Ko et al., 2002 Fogari et al., 2004 (♀) Doumas et al., 2006 (♀) Cordero et al., 2010 Ma et al., 2012 (♀) |
| Diuretics |
Croog et al.,1988 Prisant et al. 1999 Doumas et al., 2006 (♀) |
Bulpitt et al., 1973 Hogan et al., 1980 Medical Research Council,1981 Curb et al., 1985 Wassertheil-Smoller et al., 1991 Chang et al.;, 1991 Duncan et al., 1993 Rosen et al., 1999 Grimm et al., 1997 Ogihara et al., 2000 Epstein et al., 2011 |
|
| α-blockers | Grimm et al., 1997 |
Lowe et al., 1994 Fawzy et al., 1995 Lepor et al., 1997 Buchardt et al.,. 2000 Llisteri et al., 2001 McConnell et al., 2003 Kirby et al., 2003 De Rijke et al., 2004 |
|
| ACE inhibitors |
Croog et al.,1986 DiBianco et al., 1991 Gupta et al., 1995 Mancini et al., 1996 Gupta et al., 1998 |
Croog et al.,1988 Suzuki et al., 1988 Fletcher et al., 1990 Steiner et al., 1990 Pelmer et al., 1992 Grimm et al., 1997 Fogari et al., 1998 Doumas et al., 2006 (♀) |
Llisteri et al., 2001 |
| ARBs |
Fogari et al., 2001 Llisteri et al., 2001 Dusing et al., 2003 Yamamoto et al., 2003 Della Chiesa et al., 2003 Fogari et al., 2004 (♀) Ma et al., 2012 (♀) Chen et al., 2012 Segal et al., 2012 |
Suzuki et al., 1988 Rosen et al., 1994 Fogari et al., 1998 Fogari et al., 2002 Bohm et al., 2010 Doumas et al., 2006 (♀) |
|
| Calcium channel blocker |
Suzuki et al., 1988 Morrisette et al., 1993 Omvik et al., 1993 Kroner et al., 1993 Grimm et al., 1997 Ogihara et al., 2000 Burnier et al., 2007 Doumas et al., 2006 (♀) |
Tanner et al., 1988 | |
| Statins |
Saltzman et al., 2004 Herrmann et al., 2006 Dogru et al., 2008 Gokkaya et al., 2008 Dadkhah et al., 2010 |
Mastalir et al., 2011 Trivedi et al., 2012 |
|
| Cardiac glycosides |
Kley et al., 1982 Kley et al., 1984 Bellman et al., 1984 |
Stoffer et al., 1973 Neri et al., 1987 Gupta et al., 1995 |
Randomised controlled trials, double-blind crossover studies and questionnaire-based prospective studies