Table 1.
Clinical characteristics of AOA, GBMO-STS, GBMO-LTS, and GBM
| Characteristic | Subgroup 1 | P value | Subgroup 2 | P value | Subgroup 3 | P value | |||
|---|---|---|---|---|---|---|---|---|---|
| GBMO-STS (n = 11) | AOA (n = 36) | GBM (n = 110) | GBMO-STS (n = 11) | GBMO-LTS (n = 29) | GBMO-STS (n = 11) | ||||
| Age (years) | |||||||||
| Median (range) | 41.0 (14–58) | 44.0 (30–68) | 0.157 | 52.0 (12–70) | 41.0 (14–58) | 0.048* | 43.0 (17–59) | 41.0 (14–58) | 0.348 |
| Gender | |||||||||
| Male (%) | 6 (54.5) | 18 (50.0) | 70 (63.6) | 6 (54.5) | 17 (58.6) | 6 (54.5) | |||
| Female (%) | 5 (45.5) | 18 (50.0) | 0.792 | 40 (36.4) | 5 (45.5) | 0.789 | 12 (41.4) | 5 (45.5) | 1.0 |
| Tumor location | |||||||||
| Temporal (%) | 4 (36.4) | 9 (25.0) | 41 (37.3) | 4 (36.4) | 10 (34.5) | 4 (36.4) | |||
| Frontal (%) | 4 (36.4) | 15 (41.7) | 37 (33.6) | 4 (36.4) | 11 (37.9) | 4 (36.4) | |||
| Parietal (%) | 2 (18.1) | 5 (13.9) | 17 (15.5) | 2 (18.1) | 4 (13.8) | 2 (18.1) | |||
| Occipital (%) | 0 (0.0) | 1 (2.8) | 4 (3.6) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |||
| Insular (%) | 1 (9.1) | 3 (8.3) | 6 (5.5) | 1 (9.1) | 4 (13.8) | 1 (9.1) | |||
| Others (%) | 0 (0.0) | 3 (8.3) | >0.05 | 5 (4.5) | 0 (0.0) | >0.05 | 0 (0.0) | 0 (0.0) | >0.05 |
| Preoperative epilepsy | |||||||||
| Yes (%) | 3 (27.3) | 13 (36.1) | 0.859 | 25 (22.7) | 3 (27.3) | 1.0 | 5 (20.7) | 3 (27.3) | 0.791 |
| Preoperative KPS | |||||||||
| Median (range) | 80 (60–90) | 75 (50–100) | 0.768 | 80 (50–100) | 80 (60–90) | 0.369 | 80 (60–100) | 80 (60–90) | 0.677 |
| Tumor resection | |||||||||
| GTR (%) | 6 (54.5) | 25 (69.4) | 0.583 | 52 (47.3) | 6 (54.5) | 0.645 | 18 (62.1) | 6 (54.5) | 0.942 |
| Nimustine | |||||||||
| Yes (%) | 11 (100.0) | 34 (94.4) | 1.0# | 106 (96.4) | 11 (100.0) | 1.0# | 26 (89.7) | 11 (100.0) | 0.548# |
| Radiotherapy | |||||||||
| Yes (%) | 11 (100.0) | 33 (91.7) | 1.0# | 102 (92.7) | 11 (100.0) | 1.0# | 28 (96.6) | 11 (100.0) | 1.0# |
| Temozolomide | |||||||||
| Yes (%) | 7 (63.6) | 11 (30.6) | 0.105 | 59 (53.6) | 7 (63.6) | 0.525 | 21 (72.4) | 7 (63.6) | 0.877 |
KPS Karnofsky performance score, GTR gross-total resection
# Fisher’s exact test
* P < 0.05