Table 2.
Univariate and multivariate associations with survival for patients with high-grade gliomas
| Parameter | Univariate analysis | P value | Multivariate analysis | P value |
|---|---|---|---|---|
| Median survival (95 % CI) (months) | OR (95 % CI) | |||
| Factors associated with PFS | ||||
| 1p/19q co-deletion | N/A | <0.001 | 0.336 (0.176–0.643) | 0.001 |
| 1q polysomy | 9.0 (3.452–14.548) | 0.003 | – | |
| 19p polysomy | 7.0 (4.798–9.202) | <0.001 | 2.575 (1.608–4.124) | <0.001 |
| Factors associated with OS | ||||
| 1p/19q co-deletion | N/A | 0.003 | 0.319 (0.134–0.760) | 0.010 |
| 1q polysomy | 17.5 (13.404–21.596) | 0.056 | – | |
| 19p polysomy | 17.0 (13.835–20.165) | 0.009 | 1.930 (1.064–3.502) | 0.031 |
N/A not available, OR odd ratio, CI confidence interval