Fig. 1.

a Clinical efficacy of abatacept in rheumatoid arthritis patients. Mean and standard deviation for the Disease Activity Score based on 28 joints (DAS28-CRP). §p < 0.01 between the HDA and ≤MDA groups. b Changes in DAS28-CRP defined disease activity over 24 weeks of abatacept treatment. High DAS28-CRP > 4.1, Moderate 4.1 ≥ DAS28-CRP ≥ 2.7, Low 2.7 > DAS28-CRP ≥ 2.3, Remission DAS28-CRP < 2.3. c Comparison of European League Against Rheumatism (EULAR) responses at 24 weeks between patients with high disease activity at baseline (HDA) and patients with lower disease activity (≤MDA) at baseline. *p < 0.05; **p < 0.01