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Overall clinical efficacy of abatacept (ABT), adalimumab (ADA), and tocilizumab (TCZ) in rheumatoid arthritis patients with high disease activity at baseline. Mean and standard deviations for the Disease Activity Score based on 28 joints (DAS28-CRP) and tender joint count (TJC), swollen joint count (SJC), general health on a visual analogue scale (GH-VAS), c-reactive protein (CRP), and matrix metalloproteinase-3 (MMP-3) are shown
