. Author manuscript; available in PMC: 2014 Jan 13.

Published in final edited form as: Adv Space Res. 2010 Feb 26;46(6):681–686. doi: 10.1016/j.asr.2010.02.026

Table 4.

Comparisons of radiation-induced transformation between MEFs bearing different genotypes versus wild-type MEF controls. Relative transformation is defined as the ratio of the number of transformed clones per surviving heterozygous cells relative to the number of transformed clones per surviving wild-type cells. The statistical significance of differences in transformation frequency between the various cells with heterozygous genotypes and wild-type cells was analyzed by the Student's t-test.

	Atmhz/BRCA1wt	Atmwt/BRCA1hz	Atmhz/BRCA1hz
Relative transformation (0.5Gy 56Fe)	2.703	1.953	3.509

p-values	0.003	0.054	0.000083