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Effect of charged residues at position 40 on the Tyr pKa. (A) Effects of charged residues in the Asn103 background. The ΔpKa values are relative to the pKa value for Asp40Asn/Asp103Asn KSI. Values are from Table 9. (B) Effects of charged mutations in the Phe56Ala/Asp103Asn background. The number on the right at pKa zero represents the pKa for the parent form of KSI used in each comparison. Values are from Table 10.
