Table 1.
Effects of Tyr mutations on the Tyr pKa
| Mutant | pKa | ΔpKa |
|---|---|---|
| None | 7.2 | (0) |
| Tyr16Phe | >10 | >3 |
| Tyr32Phe | >9 | >2 |
| Tyr57Phe | >10 | >3 |
| Tyr16Ala | >10 | >3 |
| Tyr32Ala | >10 | >3 |
| Tyr57Ala | >10 | >3 |
None refers to Asp40Asn/Asp103Asn.
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