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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Chem Sci. 2013 Oct 9;5(1):151–155. doi: 10.1039/C3SC52572D

Figure 1.

Figure 1

Simplified schematic of quorum sensing in V. cholerae. In the absence of an agonist (i.e. at low cell density), CqsS acts as a kinase and virulence factors are expressed. When CqsS binds an agonist (stars), such as at high cell density with higher concentrations of the native agonist CAI-1 and Ea-CAI-1, CqsS acts as a phosphatase, repressing the expression of virulence factors.