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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Chem Sci. 2013 Oct 9;5(1):151–155. doi: 10.1039/C3SC52572D

Scheme 2.

Scheme 2

Variation of the Ea-CAI-1 head group: isoxazole and acylpyrrole analogs. Reagents and conditions: (a) MeMgBr, Et2O; (b) n-C9H19COCl. see Supporting Information for details on the synthesis of the acylpyrrole and isoxazole analogs.