Table 1.
Entry | EC50 (nM)a | % Responseb | |
---|---|---|---|
1 | 6, n = 4 | 590 | 100 |
2 | 7, n = 5 | 290 | 120 |
3 | 8, n = 6 | 40 | 109 |
4 | 9, n = 7 | 2.6 | 112 |
5 | Ea-CAI-1, n = 8 | 4.1 | 100 |
6 | 10, n = 9 | 170 | 105 |
7 | 11, n = 11 | >5000 | 38 |
Values were determined using the CqsS agonist bioassay.
All EC50 values are the mean of triplicate analyses.
Percent maximal bioluminescence with respect to Ea-CAI-1, which is set at 100%. For more information, see Supporting Information.