Table 1. Morphometric data of pancreatic islets in SDG-R and SDG-P mice.
Pancreas | Islet | β Cell | α Cell | |||
Weight (mg) | Density (%) | Density (%) | Mass (mg) | Density (%) | Mass (mg) | |
Before HFDa | ||||||
SDG-R | 134±9 | 0.68±0.08 | 0.59±0.06 | 0.77±0.09 | 0.091±0.022 | 0.12±0.03 |
SDG-P | 155±5 | 0.68±0.08 | 0.60±0.06 | 0.93±0.09 | 0.076±0.018 | 0.12±0.03 |
After HFDb | ||||||
SDG-R | 207±9††† | 0.92±0.08 | 0.85±0.08† | 1.77±0.22†† | 0.072±0.011 | 0.15±0.02 |
SDG-P | 302±28*,††† | 1.12±0.15† | 1.08±0.15† | 3.52±0.70**,†† | 0.039±0.004** | 0.13±0.02 |
Mean ± SEM (n = 5–6).
a Five weeks of age.
b Ten weeks of age.
*p<0.05, **p<0.01, versus SDG-R mice at the same age.
†p<0.05, ††p<0.01, †††p<0.01, versus before HFD feeding in the same line of mice.