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. 2014 Jan 13;9(1):e84688. doi: 10.1371/journal.pone.0084688

Table 6. Comparison of the diagnosis consistency of GFR stage between the eGFR and rGFR.

rGFR≥90 rGFR 60–89 rGFR<60 sum Kappa
All subjects
C-MDRD
eGFR≥90 197(87.9) 169(46.9) 7(3.4) 373
eGFR60–89 27(12.1) 162(45.0) 43(21.1) 232 0.480
eGFR<60 0 29(8.1) 154(75.5) 183
MacIsaac
eGFR≥90 131(58.5) 63(17.5) 0 194
eGFR60–89 90(40.2) 232(64.4) 31(15.2) 353 0.505
eGFR<60 3(1.3) 65(18.1) 173(84.8) 241
Ma
eGFR≥90 192(85.7) 151(41.9) 3(1.5) 346
eGFR60–89 32(14.3) 168(46.7) 40(19.6) 240 0.494
eGFR<60 0 41(11.4) 161(78.9) 202
CKD-EPI2009Scr
eGFR≥90 188(83.90) 143(39.7) 6(2.9) 337
eGFR60–89 36(16.1) 171(47.5) 41(20.1) 248 0.483
eGFR<60 0 46(12.8) 157(77.0) 203
CKD-EPI2012cys
eGFR≥90 135(60.3) 66(18.3) 0 201
eGFR60–89 79(35.3) 177(49.2) 16(7.8) 272 0.451
eGFR<60 10(4.5) 117(32.5) 188(92.2) 315
CKD-EPI2012Scr-cys
eGFR≥90 157(70.1) 91(25.3) 0 248
eGFR60–89 65(29.0) 196(54.4) 23(11.3) 284 0.513
eGFR<60 2(0.9) 73(20.3) 181(88.7) 256
Sum 224 360 204 788
Age<60 y
C-MDRD
eGFR≥90 180(88.2) 125(58.6) 4(5.3) 309
eGFR60–89 24(11.8) 83(37.6) 16(21.3) 123 0.412
eGFR<60 0 13(5.9) 55(73.3) 68
MacIsaac
eGFR≥90 126(61.8) 50(22.6) 0 176
eGFR60–89 75(36.8) 147(66.5) 16(21.3) 238 0.458
eGFR<60 3(1.5) 24(10.9) 59(78.7) 86
Ma
eGFR≥90 178(87.3) 120(54.3) 1(1.3) 299
eGFR60–89 26(12.7) 88(39.8) 19(25.3) 133 0.421
eGFR<60 0 13(5.9) 55(73.3) 68
CKD-EPI2009Scr
eGFR≥90 176(86.3) 122(55.2) 4(5.3) 302
eGFR60–89 28(13.7) 84(38.0) 19(25.3) 131 0.391
eGFR<60 0 15(6.8) 52(69.3) 67
CKD-EPI2012cys
eGFR≥90 132(64.7) 60(27.1) 0 192
eGFR60–89 65(31.9) 119(53.8) 10(13.3) 194 0.423
eGFR<60 7(3.4) 42(19.0) 65(86.7) 114
CKD-EPI2012Scr-cys
eGFR≥90 153(75.0) 79(35.7) 0 232
eGFR60–89 49(24.0) 124(56.1) 14(18.7) 187 0.478
eGFR<60 2(1.0) 18(8.1) 61(81.3) 81
Sum 204 221 75 500
Age≥60 y
C-MDRD
eGFR≥90 17(85.0) 44(31.7) 3(2.3) 64
eGFR60–89 3(15.0) 79(56.8) 27(20.9) 109 0.482
eGFR<60 0 16(11.5) 99(76.7) 115
MacIsaac
eGFR≥90 5(25.0) 13(9.4) 0 18
eGFR60–89 15(75.0) 85(61.2) 15(11.6) 115 0.481
eGFR<60 0 41(29.5) 114(88.4) 155
Ma
eGFR≥90 14(70.0) 31(22.3) 2(1.6) 47
eGFR60–89 6(30.0) 80(57.6) 21(16.3) 107 0.492
eGFR<60 0 28(20.1) 106(82.2) 134
CKD-EPI2009Scr
eGFR≥90 12(60.0) 21(15.1) 2(1.6) 35
eGFR60–89 8(40.0) 87(62.6) 22(17.1) 117 0.501
eGFR<60 0 31(22.3) 105(81.4) 136
CKD-EPI2012cys
eGFR≥90 3(15.0) 6(4.3) 0 9
eGFR60–89 14(70.0) 58(41.7) 6(4.7) 78 0.349
eGFR<60 3(15.0) 75(54.0) 123(95.3) 201
CKD-EPI2012Scr-cys
eGFR≥90 4(20.0) 12(8.6) 0 16
eGFR60–89 16(80.0) 72(51.8) 9(7.0) 97 0.431
eGFR<60 0 55(39.6) 120(93.0) 175
Sum 20 139 129 288

Note: eGFR and rGFR were given in mL/min/1.73 m2; bold font cells represent agreement; data were expressed as n (percentage).

Abbreviations: rGFR: reference glomerular filtration rate; eGFR: estimated glomerular filtration rate; C-MDRD: the Chinese modified Modification of Diet in Renal Disease equation; CKD-EPI: Chronic Kidney Disease Epidemiology Collaboration; CKD-EPI2009Scr: serum creatinine–based CKD-EPI equation which was developed in 2009; CKD-EPI2012cys: cystatin C–based CKD-EPI equation which was newly developed in 2012; CKD-EPI2012Scr-cys: serum creatinine– and cystatin C–based CKD-EPI equation which was newly developed in 2012.