Table 6. Comparison of the diagnosis consistency of GFR stage between the eGFR and rGFR.
rGFR≥90 | rGFR 60–89 | rGFR<60 | sum | Kappa | |
All subjects | |||||
C-MDRD | |||||
eGFR≥90 | 197(87.9) | 169(46.9) | 7(3.4) | 373 | |
eGFR60–89 | 27(12.1) | 162(45.0) | 43(21.1) | 232 | 0.480 |
eGFR<60 | 0 | 29(8.1) | 154(75.5) | 183 | |
MacIsaac | |||||
eGFR≥90 | 131(58.5) | 63(17.5) | 0 | 194 | |
eGFR60–89 | 90(40.2) | 232(64.4) | 31(15.2) | 353 | 0.505 |
eGFR<60 | 3(1.3) | 65(18.1) | 173(84.8) | 241 | |
Ma | |||||
eGFR≥90 | 192(85.7) | 151(41.9) | 3(1.5) | 346 | |
eGFR60–89 | 32(14.3) | 168(46.7) | 40(19.6) | 240 | 0.494 |
eGFR<60 | 0 | 41(11.4) | 161(78.9) | 202 | |
CKD-EPI2009Scr | |||||
eGFR≥90 | 188(83.90) | 143(39.7) | 6(2.9) | 337 | |
eGFR60–89 | 36(16.1) | 171(47.5) | 41(20.1) | 248 | 0.483 |
eGFR<60 | 0 | 46(12.8) | 157(77.0) | 203 | |
CKD-EPI2012cys | |||||
eGFR≥90 | 135(60.3) | 66(18.3) | 0 | 201 | |
eGFR60–89 | 79(35.3) | 177(49.2) | 16(7.8) | 272 | 0.451 |
eGFR<60 | 10(4.5) | 117(32.5) | 188(92.2) | 315 | |
CKD-EPI2012Scr-cys | |||||
eGFR≥90 | 157(70.1) | 91(25.3) | 0 | 248 | |
eGFR60–89 | 65(29.0) | 196(54.4) | 23(11.3) | 284 | 0.513 |
eGFR<60 | 2(0.9) | 73(20.3) | 181(88.7) | 256 | |
Sum | 224 | 360 | 204 | 788 | |
Age<60 y | |||||
C-MDRD | |||||
eGFR≥90 | 180(88.2) | 125(58.6) | 4(5.3) | 309 | |
eGFR60–89 | 24(11.8) | 83(37.6) | 16(21.3) | 123 | 0.412 |
eGFR<60 | 0 | 13(5.9) | 55(73.3) | 68 | |
MacIsaac | |||||
eGFR≥90 | 126(61.8) | 50(22.6) | 0 | 176 | |
eGFR60–89 | 75(36.8) | 147(66.5) | 16(21.3) | 238 | 0.458 |
eGFR<60 | 3(1.5) | 24(10.9) | 59(78.7) | 86 | |
Ma | |||||
eGFR≥90 | 178(87.3) | 120(54.3) | 1(1.3) | 299 | |
eGFR60–89 | 26(12.7) | 88(39.8) | 19(25.3) | 133 | 0.421 |
eGFR<60 | 0 | 13(5.9) | 55(73.3) | 68 | |
CKD-EPI2009Scr | |||||
eGFR≥90 | 176(86.3) | 122(55.2) | 4(5.3) | 302 | |
eGFR60–89 | 28(13.7) | 84(38.0) | 19(25.3) | 131 | 0.391 |
eGFR<60 | 0 | 15(6.8) | 52(69.3) | 67 | |
CKD-EPI2012cys | |||||
eGFR≥90 | 132(64.7) | 60(27.1) | 0 | 192 | |
eGFR60–89 | 65(31.9) | 119(53.8) | 10(13.3) | 194 | 0.423 |
eGFR<60 | 7(3.4) | 42(19.0) | 65(86.7) | 114 | |
CKD-EPI2012Scr-cys | |||||
eGFR≥90 | 153(75.0) | 79(35.7) | 0 | 232 | |
eGFR60–89 | 49(24.0) | 124(56.1) | 14(18.7) | 187 | 0.478 |
eGFR<60 | 2(1.0) | 18(8.1) | 61(81.3) | 81 | |
Sum | 204 | 221 | 75 | 500 | |
Age≥60 y | |||||
C-MDRD | |||||
eGFR≥90 | 17(85.0) | 44(31.7) | 3(2.3) | 64 | |
eGFR60–89 | 3(15.0) | 79(56.8) | 27(20.9) | 109 | 0.482 |
eGFR<60 | 0 | 16(11.5) | 99(76.7) | 115 | |
MacIsaac | |||||
eGFR≥90 | 5(25.0) | 13(9.4) | 0 | 18 | |
eGFR60–89 | 15(75.0) | 85(61.2) | 15(11.6) | 115 | 0.481 |
eGFR<60 | 0 | 41(29.5) | 114(88.4) | 155 | |
Ma | |||||
eGFR≥90 | 14(70.0) | 31(22.3) | 2(1.6) | 47 | |
eGFR60–89 | 6(30.0) | 80(57.6) | 21(16.3) | 107 | 0.492 |
eGFR<60 | 0 | 28(20.1) | 106(82.2) | 134 | |
CKD-EPI2009Scr | |||||
eGFR≥90 | 12(60.0) | 21(15.1) | 2(1.6) | 35 | |
eGFR60–89 | 8(40.0) | 87(62.6) | 22(17.1) | 117 | 0.501 |
eGFR<60 | 0 | 31(22.3) | 105(81.4) | 136 | |
CKD-EPI2012cys | |||||
eGFR≥90 | 3(15.0) | 6(4.3) | 0 | 9 | |
eGFR60–89 | 14(70.0) | 58(41.7) | 6(4.7) | 78 | 0.349 |
eGFR<60 | 3(15.0) | 75(54.0) | 123(95.3) | 201 | |
CKD-EPI2012Scr-cys | |||||
eGFR≥90 | 4(20.0) | 12(8.6) | 0 | 16 | |
eGFR60–89 | 16(80.0) | 72(51.8) | 9(7.0) | 97 | 0.431 |
eGFR<60 | 0 | 55(39.6) | 120(93.0) | 175 | |
Sum | 20 | 139 | 129 | 288 |
Note: eGFR and rGFR were given in mL/min/1.73 m2; bold font cells represent agreement; data were expressed as n (percentage).
Abbreviations: rGFR: reference glomerular filtration rate; eGFR: estimated glomerular filtration rate; C-MDRD: the Chinese modified Modification of Diet in Renal Disease equation; CKD-EPI: Chronic Kidney Disease Epidemiology Collaboration; CKD-EPI2009Scr: serum creatinine–based CKD-EPI equation which was developed in 2009; CKD-EPI2012cys: cystatin C–based CKD-EPI equation which was newly developed in 2012; CKD-EPI2012Scr-cys: serum creatinine– and cystatin C–based CKD-EPI equation which was newly developed in 2012.