Table 2. Cord plasma fatty acids in newborns of mothers with versus without gestational diabetes mellitus.
Weight (% of total fatty acids) | ||||
Control (n = 84) | GDM (n = 24) | Crude P | Adjusted P * | |
16∶0 | 28.6±3.2 | 29.4±1.9 | 0.28 | 0.13 |
18∶0 | 10.2±1.8 | 10.3±2.0 | 0.91 | 0.99 |
20∶0 | 0.5±0.1 | 0.5±0.1 | 0.97 | 0.74 |
∑ SFA | 43.5±3.4 | 44.7±2.8 | 0.10 | 0.05 |
16∶1n-7 | 3.5±0.8 | 3.6±0.7 | 0.45 | 0.48 |
18∶1n-9 | 15.5±2.0 | 15.9±1.5 | 0.31 | 0.27 |
∑MUFA | 24.5±2.2 | 25.6±2.2 | 0.03 | 0.06 |
18∶2 | 10.1±1.9 | 9.9±1.9 | 0.69 | 0.76 |
20∶3 | 2.6±0.7 | 2.5±0.5 | 0.38 | 0.28 |
20∶4 (AA) | 11.7±2.0 | 11.3±1.6 | 0.35 | 0.83 |
22∶4 | 0.6±1.9 | 0.4±0.1 | 0.60 | 0.28 |
∑n-6 PUFA | 25.8±2.5 | 24.7±2.5 | 0.06 | 0.07 |
18∶3 | 0.2±0.2 | 0.2±0.1 | 0.55 | 0.60 |
20∶5 | 0.3±0.1 | 0.2±0.1 | 0.02 | 0.03 |
22∶5 | 0.4 ± 1.9 | 0.2±0.1 | 0.54 | 0.24 |
22∶6 (DHA) | 3.5±1.1 | 2.9±0.8 | 0.01 | 0.08 |
∑n-3 PUFA | 4.4±2.1 | 3.5±0.9 | 0.04 | 0.03 |
∑n-3/∑ n-6 | 0.17±0.07 | 0.14±0.04 | 0.05 | 0.046 |
Data presented are means ± SD. GDM = gestational diabetes mellitus; SFA = saturated fatty acid; MUFA = mono-unsaturated fatty acid; PUFA = polyunsaturated fatty acid; AA = Arachidonic acid; DHA = docosahexaenoic acid.
P values adjusted for infant sex, gestational age, mode of delivery, maternal ethnicity, parity, pre-pregnancy BMI, smoking and alcohol use.
P values in bold indicate significant differences (P <0.05) comparing gestational diabetic vs. non-diabetic (control) pregnancies.