Table 3. Partial correlations between maternal and fetal/cord plasma fatty acids and between cord plasma fatty acids and indicators of fetal insulin sensitivity and beta-cell function*.
Cord plasma | Maternal plasma | Cord plasma | |||||
fatty acids | fatty acids | Glucose/insulin | Proinsulin | Proinsulin/insulin | |||
16∶0 | 0.18 | 0.02 | −0.02 | 0.05 | |||
18∶0 | 0.58c | −0.20a | 0.28b | 0.02 | |||
20∶0 | 0.40c | −0.38c | 0.39c | −0.09 | |||
∑ SFA | 0.15 | −0.15 | 0.22a | 0.06 | |||
16∶1n-7 | 0.14 | 0.03 | −0.05 | 0.07 | |||
18∶1n-9 | −0.008 | 0.02 | −0.11 | −0.11 | |||
∑ MUFA | 0.06 | −0.08 | 0.07 | −0.007 | |||
18∶2 | 0.14 | 0.19 | −0.25 b | −0.01 | |||
20∶3 | 0.28b | −0.21a | 0.16 | −0.11 | |||
20∶4 (AA) | 0.17 | −0.03 | −0.08 | −0.08 | |||
22∶4 | 0.09 | 0.11 | −0.02 | 0.07 | |||
∑ n-6 PUFA | 0.14 | 0.17 | −0.23 a | −0.04 | |||
18∶3 | 0.02 | 0.30b | −0.20a | 0.10 | |||
20∶5 | 0.53c | 0.06 | −0.15 | −0.08 | |||
22∶5 | 0.27b | 0.12 | −0.03 | 0.07 | |||
22∶6 (DHA) | 0.47c | 0.20a | −0.37c | −0.09 | |||
∑ n–3 PUFA | 0.40c | 0.24a | −0.24a | 0.03 | |||
∑ n–3/∑ n-6 | 0.55c | 0.22a | −0.23a | 0.02 |
SFA = saturated fatty acid; MUFA = mono-unsaturated fatty acid; PUFA = polyunsaturated fatty acid; AA = Arachidonic acid; DHA = docosahexaenoic acid.
Partial correlation coefficients adjusted for gestational age at blood sampling.
Correlation coefficients in bold, a P<0.05, b P <0.01, c P <0.001.