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. 2014 Jan 13;9(1):e85021. doi: 10.1371/journal.pone.0085021

Figure 5. Simplified triplet protein variants of the Prdm9 ZnF array in wild mice.

Figure 5

Sequence identifiers are highlighted with colors as in the phylogenetic tree of DNA alleles in Fig. 2 and 3. Alleles of laboratory strains previously sequenced are identified as in [12]. Each ZnF is simplified to the three most variable codons −1, 3 and 6, and separated with a dash from the next ZnF. Sequences start at the first functional C2H2 ZnF (the second repeat) and end at the last carboxy-terminal ZnF of the protein. A few remarkable stretches of zinc fingers are highlighted: some are shared between most M. musculus protein variants (QNK-QDQ, red), some are shared between the twin species spicilegus and macedonicus (QNQ-ANK-**Q-QDQ, purple), some are shared between castaneus and musculus alleles (ANQ-ESK, yellow) and some others are specific or enriched in each of domesticus (QHQ-QDK, dark blue; AVQ-AVQ, light blue), castaneus (VVQ, green), M. spretus (ADK-VNQ; QNQ-ADK, grey); M. macedonicus (QHK-QNQ, purple) and M. spicilegus (QNQ-ADK, grey) groups of alleles.