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. 2014 Jan 15;25(2):267–275. doi: 10.1091/mbc.E13-09-0541

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© 2014 Salzmann et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 6: — MR inheritance correlates with stem cell fate. (A) An example of an MR that is apparently pinched off from both sides upon GSC division in a Upd-expressing testis (nos-gal4>UAS-Upd). Green, Pav-GFP; red, Fas III and Add; blue, Vasa. The asterisk indicates hub cells. Bar, 10 μm. (B) The MR inheritance pattern in control vs. Upd-expressing testes. (C) An example of MR inherited by the cell that is displaced away from the niche (i.e., the cell at the position of the cystoblast; c587-gal4>UAS-Dpp, raised at 18°C, shifted to 29°C for 7 d). Arrowheads indicate the site of abscission. Note that Dpp expression only caused a mild increase in the GSC number under our experimental conditions. (D) The MR inheritance pattern in control vs. Dpp-expressing ovary. Only GSC-CB pairs in which the direction of MR inheritance was clear were scored.

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