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. Author manuscript; available in PMC: 2014 Aug 6.
Published in final edited form as: Anal Chem. 2013 Jul 11;85(15):7014–7018. doi: 10.1021/ac401613x

Figure 1.

Figure 1

An overview of flowprobe based mass spectrometric analysis of living microorganisms on Petri dish. (a) Schematic diagram of MS analysis of microbial colonies using a coaxial LMJ-SSP method. Solvent is continuously pumped to the surface via the outer capillary tube to extract and mobilize the molecules on the colony and aspirated into the inner capillary tube by the Venturi force generated at the nebulizer where ions are electrosprayed at the MS inlet. (b) Photograph of the flowprobe prototype platform including the x-y stage. (c) Snapshot of the flowprobe desorbing metabolites from a colony of S. coelicolor A3(2).