Table 2.
Baseline variables distributed according to plasma concentrations of YKL-40
| < 75% percentile (n = 322) | > 75% percentile (n = 171) | p-value | |
|---|---|---|---|
|
Age at index date‡ |
70 (65–75) |
72 (66–76) |
0.16 |
|
Charlson score‡* |
1 (1–2) |
1 (1–3) |
0.02 |
|
Smoking (years)‡ |
37 (26–50) |
40 (28–55) |
0.13 |
|
Neutrophils (x10^9/L)‡ |
6.2 (4.7-8.0) |
6.3 (4.9-8.9) |
0.18 |
|
FVC (L)‡ |
2.00 |
1.91 |
0.09 |
|
FEV
1
(L)‡ |
0.89 (0.69-1.15) |
0.91 (0.69-1.13) |
0.72 |
|
FEV1 predicted (%)‡ |
37.69 (29.73-47.25) |
40.68 (31.03-49.67) |
0.23 |
|
BMI‡ |
24.20 (21.04-27.83) |
24.01 (20.08-27.24) |
0.20 |
|
Present smokers§ (%) |
120 (37) |
76 (44) |
0.12 |
|
Male gender†§ (%) |
164 (51) |
83 (49) |
0.61 |
| Randomization azithromycin§ (%) | 164 (51) | 84 (49) | 0.70 |
*Significant difference using Kruskal-Wallis equality-of-populations rank test.
‡Values are median (interquartile range).
§Values are number (%).