Table 4.
Definition of causes associated with DRP
| Code | Primary domain | Code | Cause associated with DRP |
|---|---|---|---|
|
C1 |
Drug/Dose selection |
C1.1 |
Inappropriate drug selection |
| The cause of the DRP is related to the selection of the drug and/or dosage schedule | |||
| |
C1.2 |
Inappropriate dosage selection |
|
|
C1.3 |
More cost effective drugs available |
||
| |
|
C1.4 |
Pharmacokinetic problems, incl. ageing/deterioration in organ function and interactions |
| |
|
C1.5 |
Synergistic/preventive drug required and not given |
| |
|
C1.6 |
Deterioration/improvement of disease state |
| |
|
C1.7 |
New symptom or indication revealed/presented |
| |
|
C1.8 |
Manifest side effect, no other cause |
|
C2 |
Drug use process |
C2.1 |
Inappropriate timing of administration and/or dosing intervals |
| The cause of the DRP can be related to the way the patient uses the drug, in spite of proper dosage instructions (on the label) | |||
| |
|
C2.2 |
Drug underused/under-administered |
| |
|
C2.3 |
Drug overused/over-administered |
| |
|
C2.4 |
Therapeutic drug level not monitored |
| |
|
C2.5 |
Drug abused (unregulated overuse) |
| |
|
C2.6 |
Patient unable to use drug/form as directed |
|
C3 |
Information |
C3.1 |
Instructions for use/taking not known |
| The cause of the DRP can be related to a lack or misinterpretation of information | |||
| |
C3.2 |
Patient unaware of reason for drug treatment |
|
|
C3.3 |
Patients has difficulties reading patient information form/leaflet |
||
| |
|
C3.4 |
Patient unable to understand local language |
| |
|
C3.5 |
Lack of communication between healthcare professionals |
|
C4 |
Patient/Psychological |
C4.1 |
Patient forgets to use/take drug |
| The cause of the DRP can be related to the personality or behavior of the patient. | |||
| |
|
C4.2 |
Patient has concerns with drugs |
| |
|
C4.3 |
Patent suspects side-effect |
| |
|
C4.4 |
Patient unwilling to carry financial costs |
| |
|
C4.5 |
Patient unwilling to bother physician |
| |
|
C4.6 |
Patient unwilling to change drugs |
| |
|
C4.7 |
Patient unwilling to adapt life-style |
| |
|
C4.8 |
Burden of therapy |
| |
|
C4.9 |
Treatment not in line with health beliefs |
| |
|
C4.10 |
Patient takes food that interacts with drugs |
|
C5 |
Logistics |
C5.1 |
Prescribed drug not available (anymore) |
| The cause of the DRP can be related to the logistics of the prescribing or dispensing mechanism | |||
| |
|
C5.2 |
Prescribing error (only in case of slip of the pen) |
| |
|
C5.3 |
Dispensing error (wrong drug or dose dispensed) |
| |
|
C5.1 |
Prescribed drug not available (anymore) |
|
C6 |
Others |
C6.1 |
Other cause, specify |
|
C6.2 |
No obvious cause |
||
| Total |