Table 3.
Summary of subgroup analysis
|
Subgroup |
CLOSURE Trial |
PC Trial |
RESPECT Trial |
|||
|---|---|---|---|---|---|---|
| Closure | Medical | Closure | Medical | Closure | Medical | |
|
Sex (%) | ||||||
|
Male |
3.4 |
6.8 |
NA |
NA |
1.9 |
3.7 |
|
Female |
7.9 |
7.0 |
NA |
NA |
1.7 |
2.8 |
|
Atrial Septal Aneurysm (%) | ||||||
|
No |
6.2 |
7.4 |
1.9 |
5.7 |
2.2 |
2.2 |
|
Yes |
4.6 |
6.0 |
8.5 |
3.9 |
1.1 |
5.3 |
|
Age (%) | ||||||
|
≤ 45 yr |
NA |
NA |
1.1 |
6.2 |
1.7 |
2.4 |
|
> 45 yr |
NA |
NA |
5.3 |
4.4 |
1.9 |
4.1 |
|
Cardiovascular index event (%) | ||||||
|
Stroke |
5.1 |
5.1 |
3.0 |
4.9 |
NA |
NA |
|
TIA or Peripheral Embolism |
7.1 |
11.6 |
5.1 |
6.4 |
NA |
NA |
|
Shunt size (%) | ||||||
|
None to Moderate |
5.7 |
6.9 |
NA |
NA |
2.8 |
2.5 |
| Substantial | 3.5 | 4.9 | NA | NA | 0.8 | 4.3 |