Table 4.
Characteristics of genes and polymorphisms → patients (Pts) with alcoholic liver failure
|
Gene |
Allele |
rs number |
Wild type genotype |
Heterozygote genotype |
Homozygote mutation |
Pts |
|---|---|---|---|---|---|---|
| n (%) | n (%) | n (%) | ||||
| IL23R |
G/A |
11209026 |
44 (85) |
8 (15) |
|
52 |
| IL18 RAP |
A/G |
917997 |
25 (48) |
23 (44) |
4 (8) |
52 |
| CARD9 |
G/A |
4077515 |
21 (40) |
23 (44) |
8 (15) |
52 |
| NOD2 |
C/T |
2066844 |
40 (77) |
12 (23) |
|
52 |
| NOD2 |
G/C |
2066845 |
48 (80) |
10 (17) |
2(3) |
60 |
| NOD2 |
-/C |
2066847 |
47 (90) |
4 (8) |
1 (2) |
52 |
| TLR1 |
G/C |
5743611 |
32 (62) |
14 (27) |
6 (12) |
52 |
| TLR4 299 |
G/A |
4986790 |
50 (96) |
1 (2) |
1 (2) |
52 |
| TLR4 399 |
G/A |
4987233 |
48 (92) |
3 (6) |
1 (2) |
52 |
| TLR9 1237 |
C/T |
5743836 |
16 (31) |
27 (53) |
8 (16) |
51 |
| TLR9 1486 |
T/C |
187084 |
31 (61) |
19 (37) |
1 (2) |
51 |
| NQO1 609 |
C/T |
1800566 |
41 (79) |
9 (17) |
2 (4) |
52 |
| CYP1B1 432 |
G/C |
1056836 |
16 (31) |
20 (39) |
15 (30) |
51 |
| MTHFR 677 |
T/C |
1801133 |
23 (45) |
22 (43) |
6 (12) |
51 |
| MTHFR 1298 | C/A | 1801131 | 18 (41) | 23 (52) | 3 (7) | 44 |