Table 5.
Characteristics of genes and polymorphisms → patients (Pts) with non-alcoholic liver failure
|
Gene |
Allele |
rs number |
Wild type genotype |
Heterozygote genotype |
Homozygote mutation |
Pts |
|---|---|---|---|---|---|---|
| n (%) | n (%) | n (%) | ||||
| IL23R |
G/A |
11209026 |
138 (93) |
11 (7) |
|
149 |
| IL18 RAP |
A/G |
917997 |
75 (51) |
61 (41) |
12 (8) |
148 |
| Card9 |
G/A |
4077515 |
59 (40) |
67 (45) |
22 (15) |
148 |
| NOD2 |
C/T |
2066844 |
128 (86) |
|
21 (14) |
149 |
| NOD2 |
G/C |
2066845 |
138 (81) |
22 (13) |
11 (6) |
171 |
| NOD2 |
-/C |
2066847 |
145 (97) |
3 (2) |
1 (1) |
149 |
| TLR1 |
G/C |
5743611 |
82 (55) |
56 (38) |
11 (7) |
149 |
| TLR4 299 |
G/A |
4986790 |
128 (86) |
19 (13) |
2 (1) |
149 |
| TLR4 399 |
G/A |
4987233 |
130 (87) |
18 (12) |
1 (1) |
149 |
| TLR9 1237 |
C/T |
5743836 |
50 (34) |
68 (46) |
29 (20) |
147 |
| TLR9 1486 |
T/C |
187084 |
90 (61) |
47 (32) |
10 (7) |
147 |
| NQO1 609 |
C/T |
1800566 |
92 (62) |
47 (31) |
10 (7) |
149 |
| CYP1B1 432 |
G/C |
1056836 |
59 (40) |
63 (42) |
26 (18) |
148 |
| MTHFR 677 |
T/C |
1801133 |
58 (39) |
66 (45) |
23 (16) |
147 |
| MTHFR 1298 | C/A | 1801131 | 67 (53) | 42 (33) | 18 (14) | 127 |