Table 1.
Demographic & clinical information about pediatric TB suspects, N = 118
| |
Total |
Possible TB |
Probable & Culture-confirmed TB |
p-value |
|---|---|---|---|---|
| n = 118, (%) | n = 85, (%) | n = 33, (%) | ||
| Age, mean years [SD] |
4.7 [3.1] |
4.9 [3.4] |
4.4 [3.2] |
NS |
| Female gender, n (%) |
53 (45) |
39 (46) |
14 (42) |
NS |
| Mother as primary caregiver |
70 (59) |
50 (59) |
20 (61) |
NS |
| Either parent deceased |
37 (31) |
26 (31) |
11 (33) |
NS |
| HIV-infected mother |
50 (42) |
35 (41) |
15 (45) |
NS |
| Other HIV-infected family member |
9 (8) |
7 (8) |
2 (6) |
NS |
| TB contact reported |
62 (53) |
37 (44) |
25 (76) |
0.001 |
| Drug-resistant TB contact reported |
4 (3) |
3 (3) |
1 (3) |
NS |
| Contact with “chronic cougher” |
19 (16) |
13 (15) |
6 (18) |
NS |
| Prior TB |
37 (31) |
28 (33) |
9 (28) |
NS |
| Prior hospitalization (≥1) |
31 (26) |
24 (28) |
7 (21) |
NS |
| Malnourished |
52 (44) |
34 (40) |
18 (55) |
NS |
| Severely malnourished (n, % of malnourished) |
42 (81) |
26 (76) |
16 (89) |
0.09 |
| Tested for HIV |
99 (84) |
73 (86) |
26 (79) |
NS |
| HIV positive |
64 (65) |
47 (64) |
17 (65) |
NS |
| On HAART, n (% of HIV+) |
32 (50) |
25 (53) |
7 (41) |
NS |
| CD4%, median [IQR] |
16.8 [11.5-22.3] |
16.7 [13.7-22.3] |
17 [7.28-19.2] |
NS |
| Hemoglobin, median g/dL [IQR] |
9.9 [8.8-11.2] |
10.3 [9.2-11.2] |
8.9 [7.3-10.8] |
0.04 |
| Albumin, median g/L [IQR] |
32.0 [28.1-37.0] |
33.9 [29.0-37.0] |
28.8 [25.0-30.8] |
NS |
| Erythrocyte Sedimentation Rate, median [IQR] |
32.0 [14.0-75.0] |
30.0 [14.0-75.0] |
36.0 [13.5-75.0] |
NS |
| Abnormal chest radiograph consistent with TB |
84* (85) |
55* (79) |
29* (100) |
0.03 |
| Enrolled while failing ≥2 mo TB treatment |
8 (7) |
6 (7) |
2 (6) |
NS |
| Started on TB treatment | 59 (50) | 37 (44) | 22 (67) | NS |
*Of 99 children with chest radiographs available for review.