Table 1.
|
Group |
|||
---|---|---|---|---|
Control (n = 6) | UCO (n = 3) | BCO (n = 4) | BCOH (n = 4) | |
Body weight (kg) |
19.5 ± 2.8 |
17.3 ± 2.3 |
22.8 ± 3.3 |
22.0 ± 3.4 |
HR (beats/min) |
|
|
|
|
Before carotid ligation |
125 ± 15 |
112 ± 11 |
122 ± 21 |
112 ± 25 |
At brain biopsy |
111 ± 15 |
115 ± 9 |
103 ± 15 |
138 ± 16ab |
MAP (mmHg) |
|
|
|
|
Before carotid ligation |
101 ± 14 |
92 ± 4 |
105 ± 6 |
99 ± 17 |
At brain biopsy |
94 ± 11 |
85 ± 9 |
89 ± 18 |
42 ± 7ab |
Arterial pH (mmHg) |
|
|
|
|
Before carotid ligation |
7.50 ± 0.01 |
7.40 ± 0.01 |
7.53 ± 0.03 |
7.49 ± 0.06 |
At brain biopsy |
7.49 ± 0.02 |
7.52 ± 0.02 |
7.55 ± 0.04 |
7.39 ± 0.01ab |
Arterial pO2 (mmHg) |
|
|
|
|
Before carotid ligation |
107.2 ± 27.1 |
116.0 ± 48.1 |
98.3 ± 30.1 |
76.8 ± 11.6 |
At brain biopsy |
100.0 ± 15.0 |
120.0 ± 50.5 |
82.7 ± 7.3 |
71.7 ± 9.8 |
Arterial pCO2 (mmHg) |
|
|
|
|
Before carotid ligation |
38.8 ± 6.1 |
38.3 ± 7.6 |
41.0 ± 6.5 |
38.1 ± 6.3 |
At brain biopsy |
35.0 ± 8.0 |
37.0 ± 1.4 |
36.3 ± 4.6 |
41.3 ± 7.0 |
Esophageal temperature (ºC) |
|
|
|
|
Before carotid ligation |
39.3 ± 1.0 |
39.5 ± 1.0 |
38.3 ± 0.6 |
38.6 ± 0.9 |
At brain biopsy | 39.4 ± 0.9 | 39.0 ± 1.2 | 38.0 ± 0.7 | 37.8 ± 0.7 |
BCO, bilateral carotid occlusion; BCOH, bilateral carotid occlusion with systemic hypotension; MAP, mean arterial blood pressure; UCO, unilateral carotid occlusion. Values are mean ± SD. ap < 0.05 vs. before carotid ligation; bp < 0.05 vs. control.