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. 2014 Jan 14;4:515. doi: 10.3389/fimmu.2013.00515

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Copyright © 2014 Müller, Chiang, Meeths, Tesi, Entesarian, Nilsson, Wood, Nordenskjöld, Henter, Naqvi and Bryceson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Intracellular expression of CD107a, perforin, and granzyme B in patients with homozygous STX11 c.173T > C mutations. Intracellular expression of perforin, granzyme B, and CD107a was examined in patient B and C, in addition to relatives (n = 8, all four parents in addition to four siblings) as well as transport (n = 2) and local controls (n = 4). Expression of granule constituents was normalized relative to that of the transport control. Bars indicate the mean value, Error bars indicate SD.