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. 2013 Dec 1;6(6):638–648. doi: 10.1593/tlo.13640

Figure 2.

Figure 2

Cellular irradiation increases exosome release. (A) Exosome abundance was measured by NTA at 48 hours after 4-Gy treatment of GBM cells (LN18, U251, and U87MG; n = 3), GBM stem-like cells (GBAM1 and GBMJ1; n = 2), and normal astrocytes (n = 3). (B) U87MG exosomes isolated at 24 hours posttreatment with 2 to 8 Gy were measured by NTA (n = 3). (C) Measurement of exosomes released by irradiated (4 Gy) and control cells from 12 to 48 hours after treatment, relative to 0-Gy 12-hour condition (n = 3). All graphs represent averaged values relative to 0-Gy condition + SEM; values normalized to number of cells present at time of exosome isolation. *P < .05; #P < .01.