Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(A–F) Effect of metformin on the expression of mRNA for mTOR, Rheb, TSC1, TSC2, cyclin D1, and ATG2, as determined with quantitative real-time PCR. (G) Effect of metformin on the expression of ERK, pERK, cMYC, CD133, and p70-S6 proteins in PDAC. (H) Effect of metformin on IGF-1 and C-protein in the serum. Protein expression was analyzed by Western blot analysis as described in the text.
