. 2013 Dec 1;6(6):766–774. doi: 10.1593/tlo.13670

Table 1.

ROC Analysis Results at 1 or 3 Weeks Post-treatment Initiation Using Gd-VOI or FLAIR-VOI.

			Statistical															Physiological			PRM

			Tumor Volume	rCBV Mean	rCBV Median	10th	20th	25th	30th	40th	50th	60th	70th	75th	80th	90th	95th	Low rCBV	Medium rCBV	High rCBV	PRM_rCBV+	PRM_rCBV-
Week	Gd	AUC	0.640	0.408	0.424	0.565	0.540	0.538	0.520	0.464	0.424	0.418	0.410	0.422	0.408	0.383	0.381	0.542	0.472	0.451	0.513	0.743
1		P value	.113	.296	.391	.459	.647	.664	.823	.681	.391	.353	.307	.378	.296	.184	.177	.630	.751	.581	.879	.006
	FLAIR	AUC	0.615	0.607	0.569	0.551	0.576	0.588	0.602	0.598	0.569	0.582	0.592	0.605	0.625	0.615	0.625	0.638	0.573	0.588	0.518	0.727
		P value	.192	.226	.431	.565	.391	.318	.245	.264	.431	.353	.296	.404	.155	.192	.155	.118	.404	.118	.698	.010
Week	Gd	AUC	0.640	0.538	0.536	0.567	0.526	0.524	0.509	0.520	0.636	0.555	0.563	0.571	0.563	0.547	0.551	0.644	0.509	0.557	0.586	0.733
3		P value	.113	.664	.681	.445	.769	.787	.916	.623	.681	.534	.474	.418	.474	.597	.565	.102	.916	.518	.329	.008
	FLAIR	AUC	0.524	0.588	0.571	0.576	0.569	0.576	0.582	0.598	0.571	0.580	0.573	0.582	0.584	0.569	0.555	0.673	0.547	0.513	0.534	0.749
		P value	.787	.318	.418	.391	.431	.391	.353	.285	.418	.366	.404	.353	.341	.431	.534	.050	.597	.879	.698	.005

AUC and P values were generated from the ROC analysis of every metric described in Materials and Methods section (n = 20). Metrics were grouped by methods: statistically, physiologically, and PRM voxel-based approaches. Only PRM_rCBV- metrics, using either the Gd-VOI or the FLAIR-VOI and every time mid-treatment, show a statistically significant ROC analysis.