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. 2013 Dec 24;111(1):397–402. doi: 10.1073/pnas.1318843111

Fig. 2.

Fig. 2.

The effects of mutations in bfRAG1L on nuclease activity. The nuclease activities of bfRAG1L mutants on genomic DNA (A) and RNA substrates from 293T cell lines (B). (C) The nuclease activities of bfRAG1L-homologous or bfRAG1L-homologous D201A mutants of the indicated vertebrates RAG1 on genomic DNA substrate (CP, bull shark; DA, zebrafish; GG, chicken; Mus, mouse; nt, N-terminal; XL, frog). Ctrl, untreated genomic DNA substrate from 293T cell lines. The results are representative of three (A and B) or two (C) independent experiments.