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Phylogenetic analysis. (A) Scenario of VT- and NV-AANAT evolution. Blue, metazoan NV-AANAT; magenta, VT-AANAT; red branch marked with an asterisk, VT-AANAT base branch (accelerated evolution). (B) Constrained maximum likelihood tree of representative AANAT sequences. Black, nonmetazoan NV-AANAT; blue, metazoan NV-AANAT; magenta, VT-AANAT; red, VT-AANAT base branch. The scale bar indicates the number of substitutions per site.
