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. 2013 Dec 23;111(1):E194–E202. doi: 10.1073/pnas.1303317110

Fig. 5.

Fig. 5.

Distinct kinetics of long-lasting memory in extended time course after massed or spaced training. HOKR gain increase observed on day 2 in S60 (dark blue; n = 12) was maintained over a month and reduced to a level not significantly different from the initial gain on day 47 (***P < 0.001, **P < 0.01, one-way ANOVA). On the other hand, the HOKR gain in M (red; n =15) decreased on day 2 and increased again on day 5 (***P < 0.001, **P < 0.01, one-way ANOVA). The gain increase observed on day 5 in M was similar to that on day 2 in S60 (P > 0.05 vs. day 2 in S60), thus showing delayed formation of long-lasting memory by M. Gains on days 2, 10, and 15 in M showed significant difference from that on day 2 in S60 (###P < 0.001, one-way ANOVA).