Fig. 5.

Schematic representation of the mathematical models including their assumptions and fitting parameters. Four different models are presented, each with distinctive assumptions regarding each parameter. The second and third columns indicate which tetramers may form within each model and their localization coefficient (k_m). The fitting parameters are schematized using circles to represent the intrinsic permeability (p_f) of each aquaporin. In model A, a distinction was made for FaPIP2;1 intrinsic permeability; open circles represent the FaPIP2;1 intrinsic permeability when it is part of a heterotetramer, and open dotted circles represent the FaPIP2;1 intrinsic permeability when it is part of a homotetramer. The Akaike Information Criterion (AIC) value presented in the sixth column was used to analyze the goodness of fit and the complexity (number of fitting parameters) of the different models (56).