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The structure of Est3 is an OB-fold that resembles that of HsTPP1. (A) Ensemble of 10 best-scored Est3∆N structures demonstrates structural convergence. (B) Ribbon representation of the lowest energy Est3∆N structure with secondary structure elements labeled. (C) Superposition of Est3∆N (sand) and HsTPP1-OB (gray) [Protein Data Bank (PDB) ID code 2I46] with the structurally similar W/D motif highlighted. The models were prepared using PyMOL (34).
