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. Author manuscript; available in PMC: 2014 Jan 14.
Published in final edited form as: Arthritis Rheum. 2013 Nov;65(11):2898–2906. doi: 10.1002/art.38119

Figure 5.

Figure 5

Lack of association between increasing clinical activity of systemic lupus erythematosus (SLE) and a drop in the absolute numbers of FoxP3+Helios+ Treg cells, but positive correlation with an increasing percentage of FoxP3+Helios+ Treg cells among total CD4+ T cells. A and B, Percentages of FoxP3+Helios+ cells (A) and FoxP3+Helios− cells (B) in healthy donors (HD) and in SLE patients with different levels of clinical disease activity. C, Numbers of CD4+ T cells in SLE patients with different levels of clinical disease activity. D, Absolute numbers of FoxP3+Helios+ Treg cells in SLE patients with different levels of clinical disease activity. Each data point represents a single subject; bars show the mean ± SD. P values were determined by Student’s unpaired t-test.