Table 3.

Associations of CCI with factors and outcomes in the DN patients

Characteristics	Group 1 (n=234)	Group 2 (n=224)	Group 3 (n=75)	P
CCI score	1–2	3–4	≥5
Male (%)	50.0	57.6	74.7△ *	0.001
Age (year)	63±15	67±13▲	70±14△	0.000
Mogensen stage at diagnosis of DN
III stage (%)	31.2	12.9	20.0	0.000
IV stage (%)	58.5	23.2	26.7	0.000
V stage (%)	10.3	63.9	53.3	0.000
Duration of diabetes (year)	9.2±7.6	10.3±7.8▲	11.6±8.1	0.001
Hemoglobin (g/L)	122.2±22.0	111.7±22.0▲	90.9±22.7△ *	0.000
Haematocrit (L/L)	0.38±0.06	0.35±0.07▲	0.29±0.08△	0.000
Serum albumin (g/L)	35.2±4.8	34.1±7.0▲	32.2±6.4△	0.000
Urinary protein excretion (g/d)	3.33±3.16	4.46±4.40	2.84±2.17	0.082
Blood urea nitrogen (mmol/L)	6.15±3.2	7.43±3.9▲	17.15±12.7△	0.000
Serum creatinine (μmol/L)	88.4±43.0	104.6±47.1▲	317.3±280.6△ *	0.000
Triglyceride (mmol/L)	1.66±1.26	1.51±1.18	1.55±1.16	0.321
Total cholesterol (mmol/L)	4.56±1.42	4.59±1.93▲	4.34±2.00△	0.002
Low-density lipoprotein (mmol/L)	2.65±1.20	2.71±1.49▲	2.49±1.54△	0.002
High-density lipoprotein (mmol/L)	1.26±0.47	1.33±0.64	1.37±0.67	0.321
HbA1c (%)	8.5±3.70	8.4±3.30	7.3±3.13△	0.023
Mortality (%)	21.4	60.3▲	72.0△	0.000

Data are expressed as mean±SE or percentage

^△ P<0.05, compared with group 1

^▲ P<0.01, compared with group 1

^* P<0.05, compared with group 2