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COX-2 immunostaining in hyperplastic polyps and tubular adenomas of the stomach. (A) In hyperplastic polyps, no immunoreactivity was observed in epithelial cells but positive staining was observed in fibroblasts and inflammatory cells located in the upper portion of the lamina propria (×200). (B, C) Positive immunoreactivity was observed focally in the cytoplasm and perinuclear area of gastric epithelial cells in low-grade (B, ×200) and high-grade tubular adenomas (C, ×200).
