Table 2.

The rating scale used to score observed behaviors in mice. A higher score on this non-linear rating scale indicates a greater response. Scores 1–3 are normal behaviors seen in mice after saline injections, while scores 4–9 are induced by psychostimulants.

Score	Behavior Category	Included behaviors
1	Asleep/Inactive	Asleep; Awake but still
2	Light in-place directed activity	Normal grooming; Light sniffing
3	Normal exploratory behavior	Slow intermittent locomotion; Occasional rearing; Sniffing or gnawing bedding
4	Fast exploratory behavior	Continuous, fast exploratory locomotion; Increased rearing; Fast sniffing
5	Intense, in-place stereotyped behaviors	Continuous sniffing; Head bobbing/weaving; Circling/pivoting; Intense grooming/ self-gnawing
6	Patterned locomotion	Continuous running in a pattern (i.e. around periphery of box) with head up and erect tail
7	Continuous, patterned rearing	Continuous “up-and-down” motion along wall or in corner; Often licking wall
8	Maintained rear	In a full rear for entire 15-s observation bin
9	Dyskinetic/Sick	Splayed hindlimbs; Laying on side; Seizures