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. Author manuscript; available in PMC: 2014 Jan 14.
Published in final edited form as: Neuropharmacology. 2013 Apr 19;72:236–249. doi: 10.1016/j.neuropharm.2013.04.015

Table 3.

Hormone replacement in ovariectomized mice did not alter the concentration of cocaine in the brain or serum. Concentrations of brain and serum COC in Ovx mice treated with vehicle, E2, PPT, or DPN for 2 days. Brains and sera were collected 15 min after an injection of 30 mg/kg COC. Data shown as mean ± SEM. n = 7–8 animals per group.

Group
Ovx E2 PPT DPN
Brain COC (ng/g tissue) 10916 ± 646 12202 ± 367 12862 ± 2437 11174 ± 483
Serum COC (ng/mL serum) 1393 ± 324 1534 ± 339 1315 ± 252 857 ± 119