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Top: glucose infusion rate required to maintain target glucose concentrations (∼10 mM) during [1-13C]acetate infusion in healthy (□) and T2DM subjects (▲) and [U-13C]glycerol infusion in healthy subjects (gray squares). Bottom: plasma [3-3H]glucose-specific activity during [1-13C]acetate infusion in healthy (□) and T2DM subjects (▲) and [U-13C]glycerol infusion in healthy subjects (gray squares).
