Table 2.

mRNA Levels of markers of fibrosis and oxidative stress in aortae of 6 mo-old mice

	Cc1+/+	Ccl−/−
Fibrosis
Ctgf	4.86 ± 0.62	7.78 ± 1.25*
Fibronectin	0.50 ± 0.06	0.75 ± 0.08*
Tgfβ	0.87 ± 0.09	1.16 ± 0.09*
Oxidative stress
Nox4	1.11 ± 0.10	1.55 ± 0.16*

Values are expressed as means ± SE. Aortic arch was isolated from 6-mo-old male mice (n ≥ 6) to measure mRNA content by qRT-PCR (normalized to Gapdh).

^*P < 0.05 vs. Cc1^+/+.