Table 3.
Plasma and tissue biochemistry
| Cc1+/+ | Ccl−/− | |
|---|---|---|
| Plasma insulin (ng/ml) | 0.5 ± 0.1 | 1.2 ± 0.2* |
| Plasma cholesterol | ||
| Total (mg/dl) | 61.0 ± 6.8 | 61.0 ± 7.0 |
| VLDL (mg/dl) | 1.8 ± 0.6 | 3.2 ± 0.8 |
| LDL (mg/dl) | 14.0 ± 1.4 | 14.0 ± 2.3 |
| HDL (mg/dl) | 46.0 ± 5.7 | 47.0 ± 5.2 |
| Plasma triacylglycerol (TG) | ||
| Total (mg/dl) | 44.0 ± 8.2 | 39.0 ± 5.0 |
| VLDL (mg/dl) | 22.0 ± 4.5 | 22.0 ± 4.1 |
| LDL (mg/dl) | 15.0 ± 2.5 | 11.0 ± 1.5 |
| HDL (mg/dl) | 10.0 ± 2.2 | 10.0 ± 1.4 |
| Hepatic TG (μg/mg protein) | 59.0 ± 4.2 | 91.0 ± 6.3* |
| Total plasma NEFA (mEq/l) | 0.6 ± 0.1 | 1.0 ± 0.1* |
| Fatty acid composition (%) | ||
| Saturated FA | 37.7 ± 0.41 | 38.6 ± 0.33 |
| Trans-FA | 0.37 ± 0.02 | 0.36 ± 0.02 |
| Monounsaturated FA | 17.1 ± 0.44 | 19.0 ± 0.47* |
| Polyunsaturated FA | 44.9 ± 0.53 | 42.0 ± 0.58* |
| ω6-PUFA | 37.2 ± 0.46 | 34.6 ± 0.55* |
| ω3-PUFA | 7.43 ± 0.16 | 7.17 ± 0.16 |
Values are expressed as means ± SE. All triglycerides and cholesterol measurements were performed in plasma from 6 mo-old mice (n ≥ 5). Fatty acid composition was performed on n > 9–11 mice per group.
*
P < 0.05 vs. Cc1+/+.