Table 4.

mRNA levels of macrophage and inflammatory markers in aorta and white adipose tissue of 6-mo-old mice

	Cc1+/+	Ccl−/−
Aorta
VCAM-1	0.03 ± 0.01	0.06 ± 0.01†
F4/80	0.04 ± 0.01	0.11 ± 0.01†
TNFα	1.08 ± 0.31	4.78 ± 0.36†
CD3	0.02 ± 0.00	0.99 ± 0.01‡
CD4	0.01 ± 0.01	0.23 ± 0.01‡
CD8	0.02 ± 0.01	0.38 ± 0.00‡
TLR2	0.53 ± 0.06	1.07 ± 0.11‡
TLR4	0.15 ± 0.01	0.28 ± 0.04†
WAT
F4/80	1.18 ± 0.16	1.67 ± 0.16*
TNFα	0.03 ± 0.01	0.05 ± 0.01‡
IL-6	0.14 ± 0.04	0.40 ± 0.12*
IFNγ	0.04 ± 0.01	0.06 ± 0.01†
MCP-1	2.83 ± 0.16	4.79 ± 0.50†

Values are expressed as means ± SE. See text for definitions. Aortic arch was isolated from 6-mo-old male mice (n ≥ 6) to measure mRNA content by qRT-PCR (normalized to Gapdh).

^*P < 0.05,

^†P < 0.01,

^‡P < 0.001 vs. Cc1^+/+.